Tech Support: Drive not accessible, Access denied.

Drive not accessible, Access denied.

Have a Vista laptop that just quit booting.  Gets to screen about improper shutdown and whether to boot in "Safe Mode" or normal boot.  It actually won't finish booting in any mode.  Just a blank screen with an 'arrow' cursor that does move around with mouse
but that is all.
The laptop has two hard drives (each 250GB SATA).  Removed them and put the second drive in a desktop machine with Win7Pro  to see if it was accessible.
Worked just fine and copied entire contents to desktop machine.  Then tried the first drive (the C: drive)
and even though the BIOS recognizes it and it shows up in Windows Explorer, I get a "Location is not available" message box with "E:\ is not accessible.
Access is denied."
I have tried using TAKEOWN and CACLS on the drive, rebooting and I still get the same results.
As it always happens, there is some very important data that has not been backup!
Any and all help appreciated.
Steve G./N4SEG

Solutions to the Problem Drive not accessible, Access denied.

Download Error Fixer (Free)

Initialize the hdd in disk management.
Steps from this link.

http://social.technet.microsoft.com/Forums/en/w7itproperf/thread/837bb33a-d137-4965-9e1a-cc0d1b278448

The man likes to play chess; let's get him some rocks

System Update Readiness Command: To Fix Drive not accessible, Access denied.

On running the System Update readiness Command, it will Detect & Replace Incorrect Registry data with the Correct one. Which may ultimately Solve Drive not accessible, Access denied. in Windows.

1. Open CMD as Administrator by Simply Right Clicking on Start button > Command Prompt (Admin).
2. Now Type or Copy paste "DISM.exe /Online /Cleanup-image /Scanhealth" and hit Enter,
3. Now again Type or Copy paste this "DISM.exe /Online /Cleanup-image /Restorehealth" and hit Enter.
4. Close the Command Prompt Window because we are done.

Reboot your Windows & see if error Drive not accessible, Access denied. is still there.

Note: Your administrator's password might be needed.

Recommended Method to Fix the Problem: Drive not accessible, Access denied.:

How to Fix Drive not accessible, Access denied. with SmartPCFixer?

1. Click the button to download Error Fixer . Install it on your system.  Open it, and it will perform a scan for your system. The errors will be shown in the list.

2. After the scan is done, you can see the errors and problems which need to be fixed.

3. The Fixing part is done, the speed of your computer will be much higher than before and the errors have been removed.

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